{"id":15836,"date":"2023-04-27T16:31:59","date_gmt":"2023-04-27T22:31:59","guid":{"rendered":"https:\/\/anavara.com\/?post_type=treatment&#038;p=15836"},"modified":"2023-12-24T12:15:11","modified_gmt":"2023-12-24T19:15:11","slug":"spindle-cell-lipoma","status":"publish","type":"treatment","link":"https:\/\/anavara.com\/treatment\/spindle-cell-lipoma\/","title":{"rendered":"Spindle Cell Lipoma"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-introduction-nbsp\"><strong><span data-preserver-spaces=\"true\">Introduction&nbsp;<\/span><\/strong><\/h2>\n\n\n\n<p>Spindle cell lipoma (SCL), first described by Enzinger and Harvey in 1975, is a benign lesion similar to a pleomorphic lipoma. It is a rare type of lipoma that contains spindle cells and grows mostly in the subcutaneous tissues, but purely dermal tumors may also occur. It is reported in about 1.5% of all lipomatous tumors.<\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Spindle cell lipoma often develops in the back, shoulder, and posterior neck. However, there have been reported cases of its occurrence at other sites albeit, rarely. They are usually well-circumscribed.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Spindle cell lipoma as their name suggests, contains bland spindle cells, a varying mixture of mature adipocytes, and ropy collagen fibers. Histologically, there are two variants:<\/span><\/p>\n\n\n\n<ul>\n<li><span data-preserver-spaces=\"true\">The classical spindle cell lipoma which contains adipose tissues with scant spindle cell areas and<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">The fat-free variant with more spindle cells and very few fatty tissues.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-predisposition-and-causes-of-spindle-cell-lipoma\"><strong><span data-preserver-spaces=\"true\">Predisposition and Causes of Spindle Cell Lipoma<\/span><\/strong><\/h2>\n\n\n\n<p><span data-preserver-spaces=\"true\">Most spindle cell lipomas occur in adults between the ages of 40 and 60. Although men between the ages of 45 to 70 are more affected. The incidence in men and individuals assigned as male at birth is higher than in women and individuals assigned female at birth (less than 10% of cases occur in women). In people 20 years and below, the condition is rarely recorded.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Research also suggests that genetic mutations in individuals and possible inheritance for biological parents may predispose an individual to the occurrence of spindle cell lipoma.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-clinical-signs-and-symptoms\"><strong><span data-preserver-spaces=\"true\">Clinical Signs and Symptoms<\/span><\/strong><\/h2>\n\n\n\n<ul>\n<li><span data-preserver-spaces=\"true\">It usually occurs as a lump under the skin.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">May be slightly movable on palpation.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">It is usually painless.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-diagnosis-of-spindle-cell-lipoma\"><strong><span data-preserver-spaces=\"true\">Diagnosis of Spindle Cell Lipoma<\/span><\/strong><\/h2>\n\n\n\n<p><span data-preserver-spaces=\"true\">Diagnosis of spindle cell lipoma is done through<a href=\"https:\/\/anavara.com\/diagnostictest\/complete-blood-count-test\/\" target=\"_blank\"> blood work<\/a>, cytology, histology, and cytogenetics. It is also important to consider the clinical signs on presentation to the hospital.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Cytology is done via <a href=\"https:\/\/anavara.com\/diagnostictest\/core-needle-biopsy\/\" target=\"_blank\">fine needle aspiration<\/a>. The results may be as characteristic of histology. <\/span><\/p>\n\n\n\n<figure class=\"wp-block-image alignnone size-full wp-image-15838\"><img loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"288\" src=\"https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-histology.jpg\" alt=\"Spindle cell lipoma histology\" class=\"wp-image-15838\" srcset=\"https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-histology.jpg 512w, https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-histology-300x169.jpg 300w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><figcaption class=\"wp-element-caption\"><strong>Picture courtesy: <\/strong><a href=\"https:\/\/www.shutterstock.com\/image-photo\/photomicrograph-spindle-cell-lipoma-type-cells-1492639586\" rel=\"nofollow\" target=\"_blank\">Shutterstock.com<\/a><\/figcaption><\/figure>\n\n\n\n<p>However, with tumors in atypical locations, even aspirates containing all of the characteristic elements may be difficult to use for a firm diagnosis of SCL.<\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Radiographic imaging e.g. <a href=\"https:\/\/anavara.com\/diagnostictest\/mri-scan\/\" target=\"_blank\">MRI<\/a> or <a href=\"https:\/\/anavara.com\/diagnostictest\/computerized-tomography-ct-scan\/\" target=\"_blank\">CT scan,<\/a> could also serve as a means of diagnosis, especially in cases where a sarcoma is suspected.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-differential-diagnosis-of-spindle-cell-lipoma\"><strong><span data-preserver-spaces=\"true\">Differential Diagnosis of Spindle Cell Lipoma<\/span><\/strong><\/h2>\n\n\n\n<ul>\n<li><span data-preserver-spaces=\"true\">Pleomorphic lipoma: Pleomorphic lipoma and spindle cell lipoma are currently regarded as morphologic variants of a single neoplasm. The lesions are the same cytogenetically as spindle cell lipoma.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Solitary fibrous tumor: These have bland spindle cells that resemble spindle cell lipomas and ropey collagen, and they are CD34 positive. The absence of adipose tissues within the solitary fibrous tumor is helpful but may be difficult to differentiate from fat-free SCL.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Spindle cell tumors such as liposarcoma, schwannoma, neurofibroma, angiolipoma, dermatofibrosarcoma protuberans, etc.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Myxoid lesions e.g. myxoid neurofibroma, myxoma, myxoid fibrosarcoma, myxoid liposarcoma, etc.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Epidermoid cyst: In contrast to SCL, this is usually an accumulation of skin cells, fluid, pus, etc.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Sarcoidosis: This contains granulomatous growths arising from the clumping of inflammatory cells.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Subcutaneous tumors e.g. <a href=\"https:\/\/anavara.com\/treatment\/basal-cell-carcinoma-bcc-on-the-face\/\" target=\"_blank\">basal cell carcinoma<\/a>, <a href=\"https:\/\/anavara.com\/treatment\/melanoma-treatment\/\" target=\"_blank\">melanoma<\/a>, and squamous cell carcinoma.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Nodular fasciitis<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Weber-Christian panniculitis<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Erythema nodosum<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Nodular subcutaneous fat necrosis<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Vasculitic nodules: This is an inflammation of vessels that occur in response to diseases like tuberculosis or reaction to some drugs.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Rheumatoid nodules: This is an inflammation-induced swelling and occurs over joints.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Infections (e.g. onchocerciasis, loiasis)<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Haematoma: A hematoma occurs when a <a href=\"https:\/\/anavara.com\/treatment\/venous-thromboembolism-vte-dvt-or-pe\/\" target=\"_blank\">blood clot<\/a> forms in an organ, tissue, or body space following a rupture of a blood vessel.<\/span><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-management-of-spindle-cell-lipoma\"><strong><span data-preserver-spaces=\"true\">Management of Spindle Cell Lipoma<\/span><\/strong><\/h2>\n\n\n\n<p><span data-preserver-spaces=\"true\">Spindle cell lipomas are usually harmless and as such, no medical intervention may be needed. In some instances, the growth may cause discomfort in daily activities or may not be desired for aesthetic reasons.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Treatment may be non-surgical or surgical depending on the size, location, age, health status, and preference of the health practitioner. Non-excisional treatment of lipomas includes the use of steroid injections and liposuction which are more commonplace than the surgical approach.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Steroid injections into the tissues aim to cause local fat atrophy. This causes the lipoma to shrink and in very rare cases, eliminate the lesion. This is best done with SCL of less than 1-inch diameter. Lidocaine and triamcinolone acetonide are mixed in a ratio of one to one and injected into the center of the mass. This may be repeated several times every month for better effect. The major complications arise from the injections and can be minimized through a reduction in volume and proper needle placement.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\"><a href=\"https:\/\/anavara.com\/liposuction-cost\/\" target=\"_blank\">Liposuction<\/a> can be used to remove both small and large SCL especially if it is located in an area where large scars should be avoided. This can be done with a 16-gauge needle and has fewer complications than large cannula liposuction.<\/span><\/p>\n\n\n\n<p><span data-preserver-spaces=\"true\">Surgical management involves the excision of the SCL under local or general anesthesia. Surgical excision usually ensures total removal of the lipoma, unlike the other non-surgical methods of management. The patient is put under anesthesia for the procedure. The main surgery involves either an enucleation or an excision.<\/span><\/p>\n\n\n\n<ul>\n<li><strong><span data-preserver-spaces=\"true\">Enucleation<\/span><\/strong><span data-preserver-spaces=\"true\">: This is used for small lipomas. Over the lipoma, a 3 to 4-mm incision is made. Using a curette, the lipoma is freed from surrounding tissues and removed from the incision wound. No stitches are usually required rather a pressure dressing is applied to prevent hematoma formation.<\/span><\/li>\n\n\n\n<li><strong><span data-preserver-spaces=\"true\">Excision:<\/span><\/strong><span data-preserver-spaces=\"true\">&nbsp;For larger lipomas, a longer incision is made over the overlying skin and blunt dissection of the lipoma is done. It is necessary to be careful as the lipoma is sometimes highly vascularized. A stitch is used to close the incision line. <\/span><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image alignnone is-resized size-full wp-image-15839\"><img loading=\"lazy\" decoding=\"async\" width=\"887\" height=\"333\" src=\"https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-removal.jpg\" alt=\"Spindle cell lipoma removal\" class=\"wp-image-15839\" style=\"aspect-ratio:2.6636636636636637;width:593px;height:auto\" srcset=\"https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-removal.jpg 887w, https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-removal-300x113.jpg 300w, https:\/\/anavara.com\/wp-content\/uploads\/2023\/04\/Spindle-cell-lipoma-removal-768x288.jpg 768w\" sizes=\"(max-width: 887px) 100vw, 887px\" \/><figcaption class=\"wp-element-caption\"><strong>Picture courtesy: <a href=\"https:\/\/cosmetic-surgery-pune.com\/wp-content\/uploads\/2016\/12\/Lipoma-Removal.jpg\" rel=\"nofollow\" target=\"_blank\">Cosmetic Surgery Pune<\/a><\/strong><\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-complications-of-lipoma-excision\"><strong><span data-preserver-spaces=\"true\">Complications of Lipoma Excision<\/span><\/strong><\/h2>\n\n\n\n<p><span data-preserver-spaces=\"true\">The possible complications associated with the surgical management of a spindle cell lipoma include:<\/span><\/p>\n\n\n\n<ul>\n<li><span data-preserver-spaces=\"true\">Post-surgical infection especially when the procedure was done in septic conditions.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Ecchymosis due to trauma.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Injury to nearby nerves due to physical damage or anesthesia.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Injury to nearby blood vessels and possible hematoma formation.<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Permanent deformity secondary to removal of a large lesion<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Excessive scarring with cosmetic deformity or contracture<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Injury to surrounding muscle<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Fat embolus<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Periostitis\/osteomyelitis<\/span><\/li>\n\n\n\n<li><span data-preserver-spaces=\"true\">Seroma<\/span><\/li>\n<\/ul>\n\n\n\n<p><span data-preserver-spaces=\"true\">In conclusion, spindle cell lipoma is usually a non-life-threatening condition and thus, no medical intervention is required except for aesthetic reasons or when it is growing, painful, tender, or warm to touch and interfering with regular day-to-day activities.<\/span><\/p>\n<style>\r\n\r\n        .lwrp.link-whisper-related-posts{\r\n            \r\n            margin-top: 40px;\nmargin-bottom: 30px;\r\n        }\r\n        .lwrp .lwrp-title{\r\n            \r\n            \r\n        }\r\n        .lwrp .lwrp-description{\r\n            \r\n            \r\n\r\n        }\r\n        .lwrp .lwrp-list-container{\r\n        }\r\n        .lwrp .lwrp-list-multi-container{\r\n            display: flex;\r\n        }\r\n        .lwrp .lwrp-list-double{\r\n            width: 48%;\r\n        }\r\n        .lwrp .lwrp-list-triple{\r\n            width: 32%;\r\n        }\r\n        .lwrp .lwrp-list-row-container{\r\n            display: flex;\r\n            justify-content: space-between;\r\n        }\r\n        .lwrp .lwrp-list-row-container .lwrp-list-item{\r\n            width: calc(25% - 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It is a rare type of lipoma that contains spindle cells and grows mostly in the subcutaneous tissues, but purely dermal tumors may also occur. It is reported in about 1.5% of all&#8230;<\/p>\n","protected":false},"featured_media":15837,"menu_order":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"default","_kad_post_title":"default","_kad_post_layout":"default","_kad_post_sidebar_id":"","_kad_post_content_style":"default","_kad_post_vertical_padding":"default","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false},"tags":[753],"region":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.5 (Yoast SEO v22.5) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What is Spindle Cell Lipoma? 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